False color micrograph of neural stem cells in an engineered protein hydrogel.

Designing Materials to Mimic the Complexities of Living Systems

Engineering Cellular Microenvironments to Recapitulate Aging and Disease

We apply a multifaceted approach spanning polymer chemistry, protein engineering, and stem cell biology to design novel biomaterials platforms that mimic the dynamic changes in the mechanics and microstructure of the cellular environment during aging and disease progression.

Who We Are

The Madl Lab is based in the Department of Materials Science & Engineering at the University of Pennsylvania School of Engineering and Applied Sciences. We are a multidisciplinary team of materials scientists, bioengineers, chemical engineers, and cell biologists.

Interested in joining the lab or collaborating?